The Thirteenth Step by Markus Heilig

Author:Markus Heilig
Language: eng
Format: epub
Tags: MED105020, Medical/Psychiatry/Psychopharmacology, PSY038000, Psychology/Psychopathology/Addiction
Publisher: Columbia University Press
Published: 2015-05-12T04:00:00+00:00

Endophenotypes, measurable components unseen by the unaided eye along the pathway between disease and distal genotype, have emerged as an important concept in the study of complex neuropsychiatric diseases. An endophenotype may be neurophysiological, biochemical, endocrinological, neuroanatomical, cognitive, or neuropsychological (including configured self-report data) in nature. Endophenotypes represent simpler clues to genetic underpinnings than the disease syndrome itself, promoting the view that psychiatric diagnoses can be decomposed or deconstructed, which can result in more straightforward—and successful—genetic analysis.18

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